The effects of anti-VEGF and kinin B1 receptor blockade on retinal inflammation in laser-induced choroidal neovascularization.

Soumaya HachanaOlivier FontainePrzemyslaw SapiehaMark LeskRéjean Couture Elvire Vaucher

Published in: British journal of pharmacology (2020)

B1 receptor and VEGF pathways were both involved in retinal inflammation and damage in laser-induced CNV. The non-invasive, self-administration of B1 receptor antagonists on the surface of the cornea by eye drops might be an important asset for the treatment of AMD.

Keyphrases

optical coherence tomography
vascular endothelial growth factor
oxidative stress
diabetic retinopathy
optic nerve
endothelial cells
smoking cessation
replacement therapy