Genome Instability Profiles Predict Disease Outcome in a Cohort of 4,003 Patients with Breast Cancer.

Annette LischkaNatalie DobersteinSandra Freitag-WolfAyla KoçakTimo GemollKerstin Heselmeyer-HaddadThomas RiedGert AuerJens K Habermann

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)

Genome instability profiles predict disease outcome in patients with breast cancer independent of clinicopathologic parameters. This applies especially to premenopausal patients. In patients receiving adjuvant therapy, the profiles improve identification of high-risk patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
gene expression
patient reported outcomes
genome wide
postmenopausal women