Xenotransplantation of neonatal porcine bone marrow-derived mesenchymal stem cells improves murine hind limb ischemia through lymphangiogenesis and angiogenesis.
Hideaki YamadaNaoaki SakataMasuhiro NishimuraTomoko TanakaMasayuki ShimizuGumpei YoshimatsuRyo KawakamiHideichi WadaOsamu SawamotoShinichi MatsumotoShohta KodamaPublished in: Xenotransplantation (2021)
Xenotransplantation of npBM-MSCs contributed to the improvement of hind limb ischemia by both angiogenesis and lymphangiogenesis, especially promotion of the latter. npBM-MSCs may provide an alternative to autologous and allogeneic MSCs for stem cell therapy of critical limb ischemia.