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Mesenchymal stem cell therapy for laryngotracheal stenosis: A systematic review of preclinical studies.

Kathrine Kronberg JakobsenChristian GrønhøjDavid H JensenAnne Fischer-NielsenThomas HjulerChristian von Buchwald
Published in: PloS one (2017)
There may be a favorable effect of MSCs in inhibiting inflammation and as a component in tissue engineering. Given the heterogeneous nature of the included animal studies, any clear conclusion regarding the effect of tracheal stenosis in human subjects cannot be drawn. The included preclinical studies are however encouraging for further research.
Keyphrases
  • tissue engineering
  • mesenchymal stem cells
  • case control
  • endothelial cells
  • oxidative stress
  • umbilical cord
  • bone marrow
  • signaling pathway
  • induced pluripotent stem cells