Sculpting conducting nanopore size and shape through de novo protein design.
Samuel BerhanuSagardip MajumderThomas MüntenerJames WhitehouseCarolin BernerAsim K BeraAlex KangBinyong LiangG Nasir KhanBanumathi SankaranLukas K TammDavid J BrockwellSebastian HillerSheena E RadfordDavid BakerAnastassia Andreevna VorobievaPublished in: bioRxiv : the preprint server for biology (2023)
De novo design enables the generation of stable and quite transmembrane beta-barrel nanopores with tailored sizes, shapes and properties.
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