Large Hepatic Adenomas and Hepatic Adenomatosis: A Multicenter Study of Risk Factors, Interventions, and Complications.

Craig LammertEmily ToalKaran MathurVandana KhungarMichael HouseLewis R RobertsRajender K ReddyNaga Chalasani

Published in: The American journal of gastroenterology (2022)

In this large HCA cohort, obesity and metabolic comorbidities were important risk factors associated with large HCAs and adenomatosis. Long-term adverse outcomes were infrequent, 5% had tumor hemorrhage, and 1 patient exhibited malignant transformation.

Keyphrases

risk factors
metabolic syndrome
insulin resistance
type diabetes
weight loss
physical activity
case report
weight gain
high fat diet induced