Beta cell stress in a 4-year follow-up of patients with type 2 diabetes: A longitudinal analysis of the BetaDecline Study.

Giuseppina Tiziana RussoCarlo B GiordaStefania CerconeSalvatore De CosmoAntonio NicolucciDomenico Cucinottanull null

Published in: Diabetes/metabolism research and reviews (2018)

In this cohort of patients with T2DM, beta cell function progressively deteriorated despite current therapies. Among a large set of clinical and biochemical predictors, only baseline HbA1c levels and their deterioration overtime were associated with higher beta cell stress over time.

Keyphrases

single cell
cell therapy
mesenchymal stem cells
metabolic syndrome
bone marrow
heat stress
insulin resistance