Report of terbinafine resistant Trichophyton spp. in Italy: Clinical presentations, molecular identification, antifungal susceptibility testing and mutations in the squalene epoxidase gene.

Paolo BortoluzziA PrigitanoA SechiV BoneschiF GerminiasiM C EspostoL RomanòG PavanC MatinatoValentina Benzecry MancinA V MarzanoA Grancini

Published in: Mycoses (2023)

We report the first cases of terbinafine-resistant Trichophyton isolates in the Italian population. Solid antifungal management programs will be needed to promote more responsible use of antimycotics and preserve their therapeutic efficacy to control antifungal resistance.

Keyphrases

candida albicans
public health
genome wide
copy number
gene expression
single molecule
genetic diversity
bioinformatics analysis