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A systems biology approach to understand gut microbiota and host metabolism in morbid obesity: design of the BARIA Longitudinal Cohort Study.

C C Van OldenArnold W van de LaarAbraham S MeijnikmanO AydinN Van OlstJ B HoozemansL M De BrauwS C BruinY I Z AchermanJ VerheijJ E PyykköM HagedoornR SandermanN C BosmaV TremaroliA LundqvistL E OlofssonH HerremaD LappaS HjorthJ NielsenT SchwartzA K GroenM NieuwdorpF BäckhedV E A Gerdes
Published in: Journal of internal medicine (2020)
The BARIA study can add more understanding in how gut-microbiota affect metabolism, especially with regard to obesity, glucose metabolism and NAFLD. Identification of key factors may provide diagnostic and therapeutic leads to control the obesity-associated disease epidemic.
Keyphrases
  • insulin resistance
  • weight loss
  • metabolic syndrome
  • high fat diet induced
  • type diabetes
  • weight gain
  • bariatric surgery
  • adipose tissue
  • skeletal muscle
  • physical activity