Exposure-response relationship of certolizumab pegol induction and maintenance therapy in patients with Crohn's disease.

Niels Vande CasteeleB G FeaganS VermeireM YassineJ CoarseG KosuticW J Sandborn

Published in: Alimentary pharmacology & therapeutics (2017)

An exposure-response relationship was apparent for CZP in Crohn's disease and achieving higher CZP concentrations may increase the likelihood of attaining efficacy outcomes, but this remains to be evaluated prospectively.

Keyphrases

skeletal muscle
type diabetes
stem cells
metabolic syndrome
magnetic resonance
computed tomography
mesenchymal stem cells
contrast enhanced