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Monitoring anti-Xa levels in elderly medical patients undergoing thromboprophylaxis: A prospective cohort study.

Andria PapazachariouJohn A PapadakisVironas MalikidesAntigoni NikiforouDimitra AlexiadouOnoufrios MalikidesPetros IoannouMaria XimeriDiamantis P Kofteridis
Published in: Geriatrics & gerontology international (2024)
Our study reveals a substantial portion of medical elderly inpatients on thromboprophylaxis with non-prophylactic aFXa levels, with a notable prevalence among underweight and severely obese patients. Body weight, cancer, and CCI were identified as independent factors influencing aFXa levels, advocating for tailored thromboprophylaxis strategies. Further research is warranted to validate personalized dosing approaches and to enhance clinical decision-making. Geriatr Gerontol Int 2024; 24: 587-594.
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