Personalizing interventions using real-world interactions: Improving symptoms and social functioning in schizophrenia with tailored metacognitive therapy.

Kyle S MinorMatthew P MarggrafBeshaun J DavisJessica L MickensDanielle B Abel Megan L RobbinsKelly D BuckSarah E Wiehe Paul H Lysaker

Published in: Journal of consulting and clinical psychology (2021)

Compared to an evidence-based benchmark, we observed that real-world interactions can be used to tailor metacognitive therapy and improve outcomes in schizophrenia. Tailored MERIT has the potential to impact practice by personalizing treatment to account for individual variations in environment and lifestyle-aligning with the Precision Medicine Initiative-in a way that is not possible with current therapy. This is particularly salient in schizophrenia, where limited insight and cognitive deficits often make subjective reporting unreliable. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

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