Leukocyte esterase and alpha-defensin in periprosthetic joint infection: predictive quality and correlation in a prospective study.
Leonard GrünwaldFlorian SchmidutzPhilipp DöttgerFelix ErneAnna Janine SchreinerPhilipp HemmannPublished in: International orthopaedics (2023)
LE is a rapidly available alternative in PJI diagnostics. The simultaneous determination of both markers may enhance diagnostic reliability. A routine usage may shorten the time from diagnosis to treatment of PJI.
Keyphrases
- simultaneous determination
- liquid chromatography tandem mass spectrometry
- tandem mass spectrometry
- high performance liquid chromatography
- liquid chromatography
- ultra high performance liquid chromatography
- solid phase extraction
- peripheral blood
- total hip
- mass spectrometry
- ms ms
- quality improvement
- total knee arthroplasty
- high resolution
- high resolution mass spectrometry