Protective mechanisms of Taiwanese green propolis toward high glucose-induced inflammation via NLRP3 inflammasome signaling pathway in human gingival fibroblasts.
Thi Thuy Tien VoChiang-Wen LeeYao-Chang ChiangYue-Wen ChenYu-Hsiang YuVo Phuoc TuanChing-Zong WuI-Ta LeePublished in: Journal of periodontal research (2021)
Taiwanese green propolis could elicit protective effects against IL-1β-driven inflammation in high glucose-exposed HGFs through TLR2/TLR4 combined ROS/NF-κB/NLRP3 inflammasome pathway.
Keyphrases
- high glucose
- nlrp inflammasome
- endothelial cells
- signaling pathway
- oxidative stress
- toll like receptor
- inflammatory response
- pi k akt
- nuclear factor
- immune response
- lps induced
- dna damage
- induced apoptosis
- cell death
- reactive oxygen species
- diabetic rats
- induced pluripotent stem cells
- cell proliferation
- endoplasmic reticulum stress