Seroma formation after mastectomy: A systematic review and network meta-analysis of different flap fixation techniques.

Merel A Spiekerman van WeezelenburgJean H T DaemenSander M J van KuijkElisabeth R M van HaarenAlfred JanssenYvonne L J VissersGeerard L BeetsJames van Bastelaar

Published in: Journal of surgical oncology (2024)

Flap fixation is the most promising solution to prevent seroma formation after mastectomy. In this systematic review with network meta-analysis (NMA), three different techniques were compared. The NMA included 25 articles, comprising 3423 patients, and revealed that sutures are superior to tissue glue in preventing clinically significant seroma. In addition, running sutures seemed to be superior to interrupted sutures. An RCT comparing these suture techniques seems necessary, given the quality and nature of existing literature.

Keyphrases

systematic review
breast reconstruction
meta analyses
end stage renal disease
minimally invasive
newly diagnosed
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
patient reported outcomes