Basal Ti level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental perfusion model.

A GuillardE GaultierC CartierL DevoilleJ NoireauxL ChevalierM MorinF GrandinM Z LacroixC ComéraA CazanaveA de PlaceV GayrardV BachK ChardonN BekhtiK Adel-PatientC VayssièreP FisicaroN FeltinF de la FargeN Picard-HagenB LamasEric Houdeau

Published in: Particle and fibre toxicology (2020)

Altogether, these results show a materno-foetal transfer of TiO2 particles during pregnancy, with food-grade TiO2 as a potential source for foetal exposure to NPs. These data emphasize the need for risk assessment of chronic exposure to TiO2-NPs during pregnancy.

Keyphrases

human health
risk assessment
quantum dots
visible light
endothelial cells
heavy metals
electronic health record
climate change
induced pluripotent stem cells
magnetic resonance
machine learning
deep learning
oxide nanoparticles
artificial intelligence