Prognostic value of kallikrein-related peptidase 7 (KLK7) mRNA expression in advanced high-grade serous ovarian cancer.

Weiwei GongYueyang LiuEleftherios P DiamandisMarion KiechleHolger BrongerJulia DornTobias DreyerViktor Magdolen

Published in: Journal of ovarian research (2020)

The findings imply that both increased KLK5 and KLK7 mRNA expression levels represent unfavorable prognostic biomarkers in advanced high-grade serous ovarian cancer, whereby multivariate analyses indicate that KLK7 mRNA exhibits a stronger predictive value as compared to KLK5 mRNA and the combination of KLK5 and KLK7.

Keyphrases

high grade
low grade
binding protein