Evaluation of drug mechanism and efficacy of a novel anti-angiogenic agent, TTAC-0001, using multi-modality bioimaging in a mouse breast cancer orthotopic model.

Jinil KimSang Hyun ChoiSu Jung HamYoung Chul ChoSeul-I LeeJeeheon KangDong-Cheol WooWeon Sub LeeJin-San YooKyoung Won KimYoonseok Choi

Published in: PloS one (2018)

We firstly demonstrated that TTAC-0001 effectively inhibited tumor growth and neovascularization in mouse orthotopic breast cancer model. It may provide a future treatment option for breast cancer.

Keyphrases

quantum dots
vascular endothelial growth factor
current status
breast cancer risk
living cells
fluorescent probe