P2X7 Receptor and Heart Function in a Mouse Model of Systemic Inflammation Due to High Fat Diet.

Francesco RaggiChiara Rossi Francesco FaitaMariarosaria DistasoClaudia KusmicAnna Solini

Published in: Journal of inflammation research (2022)

These findings seem to suggest a cardioprotective role of P2X7R toward this tissue-specific inflammatory damage, likely through tissue homeostasis and organ functionality preservation.

Keyphrases

high fat diet
mouse model
oxidative stress
insulin resistance
adipose tissue
heart failure
atrial fibrillation
metabolic syndrome
binding protein
skeletal muscle