Durvalumab and pet-directed chemoradiation in locally advanced esophageal adenocarcinoma - a phase ib/ii study.
Darren CowzerAbraham Jing-Ching WuSmita SihagHenry S WalchBernard J ParkDavid Randolph JonesPing GuSteven B MaronRyan SugarmanSree Bhavani ChalasaniMarina ShcherbaMarinela CapanuJoanne F ChouJennie K ChoeAnton NosovPrasad S AdusumilliRandy YehLaura H TangDavid H IlsonYelena Y JanjigianDaniela MolenaGeoffrey Y KuPublished in: Annals of surgery (2023)
The addition of durvalumab to induction FOLFOX and PET directed CRT prior to surgery is safe, with a high rate of pathologic response, as well as encouraging survival data.
Keyphrases
- locally advanced
- rectal cancer
- neoadjuvant chemotherapy
- squamous cell carcinoma
- radiation therapy
- phase ii study
- positron emission tomography
- pet ct
- computed tomography
- minimally invasive
- pet imaging
- electronic health record
- big data
- lymph node
- machine learning
- cardiac resynchronization therapy
- heart failure
- coronary artery disease
- artificial intelligence
- left ventricular
- metastatic colorectal cancer
- acute coronary syndrome