Impact of catch-up vaccinations on anti-HLA antibody response in pediatric kidney transplant candidates.
Helen SweissJohn Michael LyonsKelley M K HitchmanElisabeth Lapp KincaideReed HallDaniel RanchBarrett CrowtherPublished in: Pediatric transplantation (2022)
Vaccination resulted in a transient increase in non-HLA-specific Ab. The majority of responses were non-HLA specific, hypothesized to be related to denatured antigens on single antigen beads. These data suggest limited clinical impact of vaccinations on the emergence of de novo HLA-Ab.