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Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium.

Yee-Ling WongPirro HysiGemmy CheungMilly TedjaQuan V HoangStuart W J TompsonKristina N WhisenhuntVirginie VerhoevenWanting ZhaoMoritz HessChee-Wai WongAnnette KifleyYoshikatsu HosodaAnnechien E G HaarmanSusanne HopfPanagiotis LaspasSonoko SensakiXueling SimMasahiro MiyakeAkitaka TsujikawaEcosse LamoureuxKyoko Ohno-MatsuiStefan NickelsPaul MitchellTien-Yin WongJie Jin WangChristopher J HammondVeluchamy A BarathiChing-Yu ChengKenji YamashiroTerri L YoungCaroline C W KlaverSeang Mei Sawnull null
Published in: PloS one (2019)
Of the 50 myopia-associated loci, we did not find any variant specifically associated with MMD, but the KCNMA1 and GJD2 loci were significantly associated with HM in highly myopic subjects with MMD, compared to emmetropes.
Keyphrases
  • genome wide
  • genome wide association study
  • genome wide association
  • optical coherence tomography
  • optic nerve
  • diabetic retinopathy
  • dna methylation
  • age related macular degeneration
  • cataract surgery