Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans.
Benjamin DilbergerStefan BaumannsFabian SchmittTommy SchmiedlMartin HardtUwe WenzelGunter P EckertPublished in: Oxidative medicine and cellular longevity (2019)
Using paraquat as a stressor, we here describe the association of oxidative stress, restricted energy metabolism, and reduced stress resistance and longevity in the nematode Caenorhabditis elegans making it a readily accessible in vivo model for mitochondrial dysfunction.