The use of whole exome sequencing and murine patient derived xenografts as a method of chemosensitivity testing in sarcoma.
Nicholas D CalvertJiansha WuSophie SneddonJennifer WoodhouseRichard Carey-SmithDavid WoodEvan IngleyPublished in: Clinical sarcoma research (2018)
Analysis of WES of fresh tumour specimens via a bioinformatics pipeline may identify potential actionable chemotherapy agents. Further research into this field may lead to the development of personalized cancer therapy for sarcoma.