Quetiapine ameliorates collagen-induced arthritis in mice via the suppression of the AKT and ERK signaling pathways.
Yi-Ju PanWei-Hsun WangTzu-Yao HuangWei-Hsiang WengChun-Kai FangYu-Chan ChenJeng-Jong HwangPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2018)
Taken together, these results suggest that quetiapine is a potential anti-inflammatory drug, and may be used as an adjuvant for the treatment of rheumatoid arthritis.
Keyphrases
- signaling pathway
- rheumatoid arthritis
- anti inflammatory
- pi k akt
- cell proliferation
- disease activity
- early stage
- diabetic rats
- high glucose
- induced apoptosis
- epithelial mesenchymal transition
- mouse model
- interstitial lung disease
- adipose tissue
- replacement therapy
- systemic sclerosis
- skeletal muscle
- insulin resistance
- smoking cessation
- climate change
- endoplasmic reticulum stress