Nutrient-Dependent Mitochondrial Fission Enhances Osteoblast Function.

Ciro Menale Giovanna Trinchese Immacolata AielloGiulia ScaliaMonica DenticeMaria Pina MollicaNal Ae YoonSabrina Diano

Published in: Nutrients (2023)

Our results revealed that OBs function was enhanced in the presence of glucose and PA at 25 μM. This was associated with increased OBs mitochondrial respiration and dynamics. These results suggest a role for nutrient availability in bone physiology and pathophysiology.

Keyphrases

oxidative stress
bone regeneration
single cell
type diabetes
blood glucose
metabolic syndrome
skeletal muscle
body composition
insulin resistance