Network-targeted approach and postoperative resting-state functional magnetic resonance imaging are associated with seizure outcome.

Varina L BoerwinkleEmilio G CedielLucia MireaKorwyn WilliamsJohn F KerriganSandi LamJeffrey S RaskinVirendra R DesaiAngus A WilfongP David AdelsonDaniel J Curry

Published in: Annals of neurology (2019)

Among seizure localization techniques in pediatric epilepsy, network-targeted surgery, followed by postoperative rs-fMRI normalization, has high correlation with seizure freedom. This study shows that rs-fMRI SOZ can be used as a biomarker of the epileptogenic zone, and postoperative rs-fMRI normalization is a biomarker for SOZ quiescence. ANN NEUROL 2019;86:344-356.

Keyphrases

resting state
functional connectivity
patients undergoing
magnetic resonance imaging
temporal lobe epilepsy
cancer therapy
coronary artery bypass
drug delivery
contrast enhanced
percutaneous coronary intervention
young adults
acute coronary syndrome