Metabolomics Signatures of SARS-CoV-2 Infection.
Babak ArjmandSepideh Alavi-MoghadamPeyvand Parhizkar-RoudsariMostafa Rezaei TaviraniAkram Tayanloo-BeikMahmood BiglarNeda MehrdadFereshteh Mohamadi-JahaniBagher LarijaniPublished in: Advances in experimental medicine and biology (2021)
For a very long time, viral infections have been considered as one of the most important causes of death and disability around the world. Through the viral infection, viruses as small pathogens enter the host cells and use hosts' biosynthesis machinery to replicate and collect infectious lineages. Moreover, they can modify hosts' metabolic pathways in order to their own purposes. Nowadays (in 2019-2020), the most famous type of viral infection which was caused by a novel type of coronavirus is called COVID-19 disease. It has claimed the lives of many people around the world and is a very serious threat to health. Since investigations of the effects of viruses on host metabolism using metabolomics tools may have given focuses on novel appropriate treatments, in the current review the authors highlighted the virus-host metabolic interactions and metabolomics perspective in COVID-19.
Keyphrases
- sars cov
- coronavirus disease
- mass spectrometry
- respiratory syndrome coronavirus
- induced apoptosis
- healthcare
- multiple sclerosis
- public health
- genome wide
- cell cycle arrest
- oxidative stress
- mental health
- signaling pathway
- health information
- gram negative
- gene expression
- human health
- health promotion
- risk assessment
- dna methylation