Adult-onset recurrent Kawasaki disease: an unusual cause of fever of unknown origin.
Timothy Peter Wynne JonesColin PetrieCatriona SykesPublished in: BMJ case reports (2021)
We present the case of a 20-year-old man with a background of transposition of the great arteries presenting with fever of unknown origin, who developed a shock like syndrome with respiratory failure necessitating intubation. After extensive investigation, a diagnosis of adult-onset Kawasaki disease was made, and he was successfully treated with IVIg and corticosteroids. We present the clinical findings clinicians should be aware of, and review the literature on managing this rare presentation in adult, highlighting the importance of early diagnosis in improving outcomes. Both children and adults with Kawasaki disease require long-term follow-up, as they remain at increased risk of both coronary artery aneurysms and early acute coronary syndrome.
Keyphrases
- respiratory failure
- acute coronary syndrome
- coronary artery
- case report
- extracorporeal membrane oxygenation
- mechanical ventilation
- systematic review
- young adults
- pulmonary artery
- percutaneous coronary intervention
- antiplatelet therapy
- palliative care
- acute respiratory distress syndrome
- intensive care unit
- childhood cancer
- metabolic syndrome
- type diabetes
- pulmonary hypertension
- weight loss
- adipose tissue