The cardiovascular consequences of electronic cigarette smoking: a narrative review.
Petros FountoulakisPanagiotis TheofilisSotiris TsalamandrisAlexios S AntonopoulosPanagiotis TsioufisKonstantinos ToutouzasEvangelos OikonomouKonstantinos TsioufisDimitris TousoulisPublished in: Expert review of cardiovascular therapy (2023)
Numerous studies have demonstrated that e-cigarette use can lead to acute adverse cardiovascular effects. Inhalation of e-cigarette aerosols exposes users to a wide range of potentially harmful substances that have been implicated in critical pathophysiologic pathways of cardiovascular disease, namely endothelial dysfunction, oxidative stress, inflammation, sympathetic overdrive, and arterial stiffness. While long-term epidemiological studies specifically focusing on the cardiovascular effects of e-cigarettes are still relatively scarce, early evidence suggests a potential association between e-cigarette use and an increased risk of adverse cardiovascular events. However, it is essential to recognize that e-cigarettes are relatively new products, and the full extent of their long-term cardiovascular impact has not been fully elucidated. In the meantime, promoting tobacco cessation strategies that are evidence-based and regulated, along with rigorous monitoring of e-cigarette use patterns and associated health outcomes, are essential steps in safeguarding cardiovascular health in the face of this emerging public health challenge.
Keyphrases
- smoking cessation
- cardiovascular events
- cardiovascular disease
- oxidative stress
- public health
- coronary artery disease
- replacement therapy
- blood pressure
- emergency department
- liver failure
- case control
- hepatitis b virus
- drinking water
- metabolic syndrome
- intensive care unit
- drug induced
- induced apoptosis
- electronic health record
- endoplasmic reticulum stress