A novel glycopeptide from mountain-cultivated ginseng residue protects type 2 diabetic symptoms-induced heart failure.

Zhuoran LiDongyue ZhouTongchuan WuHyogeun LeeFei ZhengYulin DaiHao Yue

Published in: Journal of ethnopharmacology (2024)

APMCG-1 protects PA-induced H9c2 cells while reducing cardiac dysfunction in zebrafish with type 2 diabetic symptoms. The present study provides a new insight into the development of natural glycopeptides as heart-related drug therapies.

Keyphrases

heart failure
high glucose
diabetic rats
drug induced
type diabetes
induced apoptosis
left ventricular
oxidative stress
atrial fibrillation
endothelial cells
cell cycle arrest
emergency department
cell death
physical activity
signaling pathway
cardiac resynchronization therapy
endoplasmic reticulum stress