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Association of endothelial nitric oxide synthase (NOS3) gene polymorphisms with primary open-angle glaucoma in a Saudi cohort.

Altaf A KondkarTaif A AzadTahira SultanEssam A OsmanFaisal A AlmobarakSaleh A Al-Obeidan
Published in: PloS one (2020)
Our results suggest that the polymorphism rs1799983 and the haplotypes of rs20707440 and rs1799983 in the NOS3 gene may significantly modulate the risk of POAG in Saudi's, particularly among men. Further larger studies are needed to confirm these findings.
Keyphrases
  • nitric oxide synthase
  • nitric oxide
  • saudi arabia
  • endothelial cells
  • genome wide
  • gene expression
  • case control
  • genome wide analysis