Association of rare, recurrent nonsynonymous variants in the germline of prostate cancer patients of African ancestry.

Jun WeiJennifer Beebe-DimmerZhuqing ShiChristopher SampleGuifang YanAndrew S RifkinAzita SadeghpourMarta GielzakSodam ChoiDavid MoonS Lilly ZhengBrian T HelfandPatrick C WalshJianfeng XuKathleen A CooneyWilliam B Isaacs

Published in: The Prostate (2022)

This WES study identified two rare, recurrent nonsynonymous PCa risk-associated variants in AA. Confirmation in additional large populations of AA PCa cases and controls is required.

Keyphrases

copy number
prostate cancer
dna repair
gene expression
benign prostatic hyperplasia
oxidative stress
dna damage
genome wide