Solid and Hematologic Neoplasms After Testicular Cancer: A US Population-Based Study of 24 900 Survivors.
Michael T MilanoPaul C DinhHongmei YangMohammad Abu ZaidSophie D FossåDarren R FeldmanPatrick O MonahanLois B TravisChunkit FungPublished in: JNCI cancer spectrum (2020)
We report statistically significant excesses of solid-SMN affecting 1 in 6 TCS 30 years after radiotherapy, and 2.7-fold risks of leukemias after chemotherapy, mostly acute myeloid leukemia. Efforts to minimize chemotherapy and radiotherapy exposures for TC should continue. TCS should be counseled about cancer prevention and screening.
Keyphrases
- locally advanced
- papillary thyroid
- acute myeloid leukemia
- early stage
- squamous cell
- radiation therapy
- rectal cancer
- squamous cell carcinoma
- radiation induced
- young adults
- risk assessment
- childhood cancer
- human health
- allogeneic hematopoietic stem cell transplantation
- acute lymphoblastic leukemia
- quality improvement
- germ cell