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Levodopa-induced dyskinesia in early-onset Parkinson's disease (EOPD) associates with glucocerebrosidase mutation: A next-generation sequencing study in EOPD patients in Thailand.

Sekh ThanprasertsukPrasit PhowthongkumThitipong HopetrungraungChalalai PoorirerngpoomTikumphorn SathirapatyaPatsorn WichitOnanong PhokaewvarangkulKornkiat VongpaisarnsinSaknan Bongsebandhu-PhubhakdiRoongroj Bhidayasiri
Published in: PloS one (2023)
Our study highlights the high prevalence of GBA pathogenic variants in Thai patients with EOPD and the independent association of these variants with the earlier onset of LID. This emphasizes the importance of genetic testing in this population.
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