Ion Mobility Spectrometry in Food Analysis: Principles, Current Applications and Future Trends.
Maykel Hernández-MesaDavid RopartzAna M García-CampañaHélène RogniauxGaud Dervilly-PinelAbdoulaye Zié KonéPublished in: Molecules (Basel, Switzerland) (2019)
In the last decade, ion mobility spectrometry (IMS) has reemerged as an analytical separation technique, especially due to the commercialization of ion mobility mass spectrometers. Its applicability has been extended beyond classical applications such as the determination of chemical warfare agents and nowadays it is widely used for the characterization of biomolecules (e.g., proteins, glycans, lipids, etc.) and, more recently, of small molecules (e.g., metabolites, xenobiotics, etc.). Following this trend, the interest in this technique is growing among researchers from different fields including food science. Several advantages are attributed to IMS when integrated in traditional liquid chromatography (LC) and gas chromatography (GC) mass spectrometry (MS) workflows: (1) it improves method selectivity by providing an additional separation dimension that allows the separation of isobaric and isomeric compounds; (2) it increases method sensitivity by isolating the compounds of interest from background noise; (3) and it provides complementary information to mass spectra and retention time, the so-called collision cross section (CCS), so compounds can be identified with more confidence, either in targeted or non-targeted approaches. In this context, the number of applications focused on food analysis has increased exponentially in the last few years. This review provides an overview of the current status of IMS technology and its applicability in different areas of food analysis (i.e., food composition, process control, authentication, adulteration and safety).
Keyphrases
- liquid chromatography
- mass spectrometry
- gas chromatography
- tandem mass spectrometry
- high resolution mass spectrometry
- solid phase extraction
- current status
- high resolution
- high performance liquid chromatography
- simultaneous determination
- human health
- gas chromatography mass spectrometry
- ms ms
- multiple sclerosis
- healthcare
- cancer therapy
- health information
- molecular dynamics