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Novel complex of cosmetic ingredients with promising action in preventing hair loss and follicular aging through mechanism involving enrichment of WNT/signaling, mitochondrial activity, and stem cells maintenance.

Mamy Honda IgarashiSheila Gomes da SilvaMaurizio MercuriFlávia Macedo de Oliveira Neves ZuardiGustavo FacchiniGustavo Henrique da SilvaAna Lucia Tabarini Alves PinheiroSamara Eberlin
Published in: Journal of cosmetic dermatology (2020)
The integral effects of AcPi have not been completely elucidated; however, these results, associated with clinical evidences, allow us to infer that this ingredient prevents follicular aging, miniaturization, and consequently hair loss by mechanisms involving energetic homeostasis maintenance, antioxidant, and anti-androgenic actions.
Keyphrases
  • stem cells
  • oxidative stress
  • cell therapy
  • mouse model