Alkynyl Borrowing: Silver-Catalyzed Amination of Secondary Propargylic Alcohols via C(sp 3 )-C(sp) Bond Cleavage.

Xin ZhuangMin ZhuChuan-Ming HongZhen LuoWan-Fang LiQing-Hua LiQun-Li Luo Tang-Lin Liu

Published in: The Journal of organic chemistry (2022)

The silver-catalyzed alkynyl borrowing amination of secondary propargyl alcohols via C(sp 3 )-C(sp) bond cleavage has been developed. This new strategy was based on the β-alkynyl elimination of propargyl alcohols and alkynyl as the borrowing subject. This alkynyl borrowing amination featured high atom economy, wide functional group tolerance, and high efficiency.

Keyphrases

high efficiency
gold nanoparticles
room temperature
dna binding
silver nanoparticles
molecular dynamics
transcription factor
electron transfer