Alkynyl Borrowing: Silver-Catalyzed Amination of Secondary Propargylic Alcohols via C(sp 3 )-C(sp) Bond Cleavage.
Xin ZhuangMin ZhuChuan-Ming HongZhen LuoWan-Fang LiQing-Hua LiQun-Li LuoTang-Lin LiuPublished in: The Journal of organic chemistry (2022)
The silver-catalyzed alkynyl borrowing amination of secondary propargyl alcohols via C(sp 3 )-C(sp) bond cleavage has been developed. This new strategy was based on the β-alkynyl elimination of propargyl alcohols and alkynyl as the borrowing subject. This alkynyl borrowing amination featured high atom economy, wide functional group tolerance, and high efficiency.