Transition to secondary progression in relapsing-onset multiple sclerosis: Definitions and risk factors.

Pietro IaffaldanoGiuseppe LucisanoFrancesco PattiVincenzo Brescia MorraGiovanna De LucaAlessandra LugaresiMauro ZaffaroniMatilde IngleseGiuseppe SalemiEleonora CoccoAntonella ConteDiana FerraroSimonetta GalganiRoberto BergamaschiCarlo PozzilliMarco SalvettiGiacomo LusMarco Rovaris Giorgia Teresa ManiscalcoFrancesco Ottavio LogulloDamiano PaolicelliMariaclara AchilleGiuseppina MarrazzoValeria LovatoGiancarlo ComiMassimo FilippiMaria Pia AmatoMaria Trojanonull null

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)

A DDA definition of SPMS identifies more aggressive progressive patients. DMT exposure reduces the risk of SPMS conversion, but it does not prevent the disability accumulation after the SP transition.

Keyphrases

multiple sclerosis
risk factors
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
rheumatoid arthritis
patient reported outcomes