Brain Injury in Neonates with Complex Congenital Heart Disease: What Is the Predictive Value of MRI in the Fetal Period?
Marie Brossard-RacineAdre J du PlessisGilbert VezinaRichard D RobertsonMary T DonofrioWayne TworetzkyCatherine LimperopoulosPublished in: AJNR. American journal of neuroradiology (2016)
Brain abnormalities detected by in utero MR imaging in fetuses with congenital heart disease are associated with higher risk of postnatal preoperative brain injury. However, a substantial proportion of anomalies on postnatal MR imaging were not present on fetal MR imaging; this result is likely due to the limitations of conventional fetal MR imaging and the emergence of new lesions that occurred after the fetal studies. Postnatal brain MR imaging studies are needed to confirm the presence of injury before open heart surgery.
Keyphrases
- brain injury
- contrast enhanced
- subarachnoid hemorrhage
- cerebral ischemia
- congenital heart disease
- magnetic resonance imaging
- preterm infants
- minimally invasive
- magnetic resonance
- computed tomography
- resting state
- heart failure
- diffusion weighted imaging
- atrial fibrillation
- functional connectivity
- blood brain barrier