Bo-Gan-Whan regulates proliferation and migration of vascular smooth muscle cells.

Kang Pa LeeJai-Eun KimHyuck KimHae Ryong ChangDae Won LeeWon-Hwan Park

Published in: BMC complementary and alternative medicine (2016)

We suggest that BGH may have an anti-atherosclerosis effect by inhibiting the proliferation and migration of PDGF-BB-stimulated VSMCs through down-regulation of ERK1/2 and p38 MAPK phosphorylation.

Keyphrases

vascular smooth muscle cells
angiotensin ii
signaling pathway
cardiovascular disease
cell proliferation
growth factor
pi k akt
type diabetes
protein kinase
recombinant human
smooth muscle