Selective Inhibition of PI3K Isoforms in Brain Tumors Suppresses Tumor Growth by Increasing Radiosensitivity.
Mi Youn SeolSeo Hee ChoiIk Jae LeeHyung Soon ParkHye Ryun KimSang-Kyum KimHong In YoonPublished in: Yonsei medical journal (2023)
This study verified that PI3K-α isoform inhibition improves radiosensitivity, resulting in tumor growth suppression and extended survival in GBM mice.