Effect of the interaction between advanced maternal age and pre-pregnancy BMI on pre-eclampsia and GDM in Central China.

Mengting SunManjun LuoTingting WangJianhui WeiSenmao ZhangJing ShuTaowei ZhongYiping LiuQian ChenPing ZhuJiabi Qin

Published in: BMJ open diabetes research & care (2023)

Advanced maternal age and pre-pregnancy BMI were respectively associated with the risk of pre-eclampsia/GDM, and there was an interaction between the two risk factors. In addition, we found that pre-pregnancy BMI served as a mediator of the association between advanced maternal age and the risk of pre-eclampsia/GDM, providing an essential target for the prevention of maternal overweight/obesity.

Keyphrases

pregnancy outcomes
weight gain
birth weight
body mass index
pregnant women
risk factors
preterm birth
weight loss
type diabetes
metabolic syndrome
gestational age