Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.

Yi QueXiao-Long ZhangZe-Xian LiuJing-Jing ZhaoQiu-Zhong PanXi-Zhi WenWei XiaoBu-Shu XuDong-Chun HongTian-Hui GuoLu-Jun ShenWei-Jun FanHuo-Ying ChenDe-Sheng WengHai-Rong XuPeng-Hui ZhouYi-Zhuo ZhangXiao-Hui NiuXing Zhang

Published in: Journal for immunotherapy of cancer (2021)

The combination of chidamide and anti-programmed cell death 1 (PD-1) therapy represents a potentially important strategy for STS.

Keyphrases

bioinformatics analysis
histone deacetylase
nucleic acid
gene expression
bone marrow
genome wide identification