Uterine Artery Doppler Ultrasonography for First Trimester Prediction of Preeclampsia in Individuals at Risk from Low-Resource Settings.
Mihaela OanceaMihaela GrigoreRazvan CiorteaDoru DiculescuDiana BodeanCarmen BucuriȘtefan StrilciucMaria RadaDan MihuPublished in: Medicina (Kaunas, Lithuania) (2020)
Background and objectives: The objective of this study was to evaluate the potential of first trimester uterine artery Doppler ultrasonography for the early prediction of preeclampsia (PE), in at-risk pregnant women. Materials and Methods: This was a prospective longitudinal study, including 120 Caucasian pregnant women with risk factors for PE. The potential of pulsatility indexes (PI) and notch was assessed as a tool for preeclampsia screening. Results: Doppler examination of the uterine artery performed early at 11-14 WA allows the detection of pregnancies that will develop PE with a sensitivity of 61.5% and a specificity of 63.8% based on PI analysis. Predictive power increases slightly by adding bilateral notch (sensitivity = 65.4%; specificity = 66%). Conclusions: Uterine artery Doppler examination is an effective non-invasive screening test for the development of PE in pregnancies at risk, particularly appropriate in health systems with limited means of evaluating other biomarkers.
Keyphrases
- pregnant women
- pregnancy outcomes
- early onset
- blood flow
- magnetic resonance imaging
- public health
- healthcare
- contrast enhanced
- preterm birth
- cell proliferation
- human health
- risk assessment
- computed tomography
- health information
- gestational age
- magnetic resonance
- sensitive detection
- social media
- real time pcr
- structural basis