Serum levels of miR-223 but not miR-21 are decreased in patients with neuroendocrine tumors.
Teresa HellbergRaphael MohrLukas GeislerJana KnorrAlexander WreeMünevver DemirFabian BenzJoeri LambrechtSven H LoosenFrank TackeChristoph RoderburgHenning JannBurcin ÖzdirikPublished in: PloS one (2020)
Lower concentrations of circulating miR-223 rather reflect the presence of NET itself than certain tumor characteristics. The value of miR-223 as a biomarker in NET might be limited to diagnostic, but not prognostic purposes.