The molecular evolutionary characteristics of new isolated H9N2 AIV from East China and the function of vimentin on virus replication in MDCK cells.

Yuan Nan YuYang ZhengShan Shan HaoZe ZhangJia Xi CaiMan Man ZongXiu Li FengQing Tao Liu

Published in: Virology journal (2020)

These findings suggested that the isolated H9N2 AIV might be a recent clinical common H9N2 strain, and vimentin protein might be one vital factor for H9N2 AIV replication in MDCK cells, which might be a novel target for design and development of antiviral drug.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
gene expression
emergency department
oxidative stress
small molecule
genome wide
pi k akt
drug induced