Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models.

Matteo CentonzeGiusy Di ConzaMichael LahnIsabel FabregatFrancesco DituriIsabella GiganteGrazia SerinoRosanna ScialpiLivianna CarrieriRoberto NegroElena PizzutoGianluigi Giannelli

Published in: Journal of experimental & clinical cancer research : CR (2023)

These results indicate that IOA-289 may be an effective drug for the treatment of tumors of the gastrointestinal tract, particularly those characterized by a high degree of fibrosis.

Keyphrases

papillary thyroid
squamous cell
stem cells
squamous cell carcinoma
cell therapy
emergency department
bone marrow
childhood cancer