PD-L1 as a Urine Biomarker in Renal Cell Carcinoma-A Case Series and Proof-of-Concept Study.
Philipp ReimoldGeorgi TosevAdam KaczorowskiJana FriedhoffConstantin SchwabViktoria SchützMagdalena GoertzNiklas PanzerMartina HellerCem AksoyRuth HimmelsbachThomas WalleStefanie ZschäbitzDirk JägerAnette U DuensingAlbrecht StenzingerMarkus HohenfellnerStefan DuensingPublished in: Diagnostics (Basel, Switzerland) (2024)
In this proof-of-concept study, we show that PD-L1 can be detected in the urine of RCC patients. Urine PD-L1 levels were found to correlate with the treatment response in mRCC patients and were significantly elevated in treatment-naïve RCC patients.