Potential biomarkers in patients with systemic sclerosis.

Andrea Delle SedieLucrezia RienteLavinia MaggioriniFederico PratesiAntonio TavoniPaola MiglioriniIlaria Puxeddu

Published in: International journal of rheumatic diseases (2017)

Endostatin, elastase and the soluble adhesion molecules (sICAM-1 and sVCAM-1) are potentially involved in the pathogenesis of SSc. Moreover, the significant correlation observed between sICAM-1 and CRP and ESR indicates that sICAM-1 might be a useful biomarker of the inflammatory state of the disease.

Keyphrases

systemic sclerosis
interstitial lung disease
oxidative stress
estrogen receptor
rheumatoid arthritis
recombinant human
cell migration
idiopathic pulmonary fibrosis